Title: RNA Interference
Author(s): Patrick Paddison, Peter K. Vogt
Series: Current Topics in Microbiology and Immunology, vol.320
Publisher: Springer
ISBN: 3540751564
Publication: 2008
Pages: 276
Description: In the last few years the major effect that RNAi has had in invertebrate systems like C.elegans and drosophila is beginning to take hold in mammalian systems through both single gene knockdown experiments and genome-scale screens. In the next decade, there will no doubt be both notable successes and failures as we attempt to apply this genetic tool to various biological problems for the first time in academia and industry. Through the introduction of RNAi, mammalian systems have finally gained admittance to the pantheon of model genetic systems. 